For an annual fee “Prime Student” gives subscribers discounts, free delivery and access to Amazon’s video streaming.
Wells Fargo is one of the largest providers of student loans in the US.
The deal should help the bank promote products and Amazon attract students.
“Prime Student” subscribers will be eligible for a 0.5% discount on Wells Fargo student loans.
In a statement, Wells Fargo’s head of personal lending John Rasmussen said: “We are focused on innovation and meeting our customers where they are – and increasingly that is in the digital space”.